Motif ID: NANOG{mouse}.p2

Z-value: 0.991


Transcription factors associated with NANOG{mouse}.p2:

Gene SymbolEntrez IDGene Name
NANOG 79923 Nanog homeobox

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NANOGchr12_+_78332920.332.1e-01Click!


Activity profile for motif NANOG{mouse}.p2.

activity profile for motif NANOG{mouse}.p2


Sorted Z-values histogram for motif NANOG{mouse}.p2

Sorted Z-values for motif NANOG{mouse}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NANOG{mouse}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_121780835 1.603 NM_032554
GPR81
G protein-coupled receptor 81
chr12_-_121753795 1.322 NM_177551
GPR109A
G protein-coupled receptor 109A
chr3_-_56784634 1.226 NM_001128616
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr7_-_143523582 1.035 NM_001003702
ARHGEF35
Rho guanine nucleotide exchange factor (GEF) 35
chr7_-_143622233 1.016 ARHGEF35
Rho guanine nucleotide exchange factor (GEF) 35
chr7_+_143683365 1.009 NM_005435
ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr6_+_148705421 0.982 NM_015278
SASH1
SAM and SH3 domain containing 1
chr10_-_48010879 0.980 NM_002900
RBP3
retinol binding protein 3, interstitial
chr1_+_208472817 0.959 NM_019605
SERTAD4
SERTA domain containing 4
chr7_-_143622188 0.955 ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr15_-_29734833 0.857 NM_130901
OTUD7A
OTU domain containing 7A
chr12_-_121767272 0.758 NM_006018
GPR109B
G protein-coupled receptor 109B
chr1_+_44643513 0.748 NM_018150
RNF220
ring finger protein 220
chr4_-_15686838 0.737 NM_001145849
NM_001145850
NM_001145851
NM_001145852
NM_006017
PROM1




prominin 1




chr16_-_3025542 0.686 NM_001103175
CCDC64B
coiled-coil domain containing 64B
chr1_+_20338405 0.608 NM_022819
PLA2G2F
phospholipase A2, group IIF
chr2_+_64535114 0.554 HSPC159
galectin-related protein
chr7_+_143646150 0.537 NM_001005287
NM_001001802
OR2A1
OR2A42
olfactory receptor, family 2, subfamily A, member 1
olfactory receptor, family 2, subfamily A, member 42
chr10_+_123912930 0.531 TACC2
transforming, acidic coiled-coil containing protein 2
chr15_-_76313896 0.526 NM_015162
ACSBG1
acyl-CoA synthetase bubblegum family member 1
chr3_+_46594079 0.524 NM_003212
TDGF1
teratocarcinoma-derived growth factor 1
chr1_-_54256390 0.522 NM_001010978
LDLRAD1
low density lipoprotein receptor class A domain containing 1
chr22_+_35777561 0.515 NM_024681
KCTD17
potassium channel tetramerisation domain containing 17
chr10_+_80942362 0.503 NM_001099692
EIF5AL1
eukaryotic translation initiation factor 5A-like 1
chr7_+_134226727 0.497 CALD1
caldesmon 1
chr1_+_204484081 0.491 NM_001910
NM_148964
CTSE

cathepsin E

chr1_-_199732323 0.486 NM_001193572
CSRP1
cysteine and glycine-rich protein 1
chrX_-_119898692 0.482 NM_173571
NM_001080137
NM_001080138
NM_001080139
NM_001080141
NM_001080142
NM_001080143
NM_001080144
NM_001080145
NM_001080146
CT47A11
CT47A10
CT47A9
CT47A8
CT47A6
CT47A5
CT47A4
CT47A3
CT47A2
CT47A1
cancer/testis antigen family 47, member A11
cancer/testis antigen family 47, member A10
cancer/testis antigen family 47, member A9
cancer/testis antigen family 47, member A8
cancer/testis antigen family 47, member A6
cancer/testis antigen family 47, member A5
cancer/testis antigen family 47, member A4
cancer/testis antigen family 47, member A3
cancer/testis antigen family 47, member A2
cancer/testis antigen family 47, member A1
chr6_+_148705646 0.477 SASH1
SAM and SH3 domain containing 1
chr12_+_10222823 0.453 NM_153022
C12orf59
chromosome 12 open reading frame 59
chr15_+_87540238 0.452 ABHD2
abhydrolase domain containing 2
chr16_+_8675904 0.446 NM_020686
ABAT
4-aminobutyrate aminotransferase
chr5_-_33928049 0.441 ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr3_-_46761248 0.428 NM_199183
PRSS45
protease, serine, 45
chr5_-_138767654 0.427 NM_194296
SPATA24
spermatogenesis associated 24
chr7_+_150013716 0.425 NM_015660
GIMAP2
GTPase, IMAP family member 2
chr12_-_49763405 0.421 CSRNP2
cysteine-serine-rich nuclear protein 2
chr5_-_39400319 0.417 NM_001737
C9
complement component 9
chr7_+_30704125 0.417 INMT
indolethylamine N-methyltransferase
chr3_-_69381995 0.405 FRMD4B
FERM domain containing 4B
chr20_+_55718718 0.398


chr6_+_31647854 0.397 NM_001159740
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr6_+_116956868 0.396 NM_153036
FAM26D
family with sequence similarity 26, member D
chr2_+_84597087 0.396 NM_001370
DNAH6
dynein, axonemal, heavy chain 6
chr1_+_43508251 0.386 NM_144626
TMEM125
transmembrane protein 125
chr6_-_43531763 0.381 NM_206539
DLK2
delta-like 2 homolog (Drosophila)
chr3_+_32123140 0.378 GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr19_+_15058790 0.371 NM_001004713
OR1I1
olfactory receptor, family 1, subfamily I, member 1
chr1_-_246857051 0.366 NM_001001964
OR2T11
olfactory receptor, family 2, subfamily T, member 11
chr17_-_74085070 0.358 NM_173628
DNAH17
dynein, axonemal, heavy chain 17
chr4_-_82345224 0.355 NM_006259
PRKG2
protein kinase, cGMP-dependent, type II
chrX_+_103243762 0.344 NM_001143978
ZCCHC18
zinc finger, CCHC domain containing 18
chr7_+_150180510 0.343 ABP1
amiloride binding protein 1 (amine oxidase (copper-containing))
chr10_+_18729518 0.343 NM_201570
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr10_+_69314347 0.339 NM_012238
SIRT1
sirtuin 1
chr11_+_120966280 0.336 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr20_+_55718619 0.333


chr22_+_43527101 0.332 NM_001017526
NM_001198726
NM_181335
ARHGAP8


Rho GTPase activating protein 8


chr2_-_21084077 0.332 APOB
apolipoprotein B (including Ag(x) antigen)
chr7_-_28186867 0.328 NM_175061
JAZF1
JAZF zinc finger 1
chrX_+_2680092 0.327 NM_001141919
NM_001141920
NM_175569
XGPY2
XG


Xg pseudogene, Y-linked 2
Xg blood group


chr11_-_85146691 0.323 NM_001162951
NM_001162953
SYTL2

synaptotagmin-like 2

chr1_-_204011166 0.320 NM_001135662
NM_001135663
NM_001135664
NM_003929
RAB7L1



RAB7, member RAS oncogene family-like 1



chr4_-_153820535 0.319 NM_152680
TMEM154
transmembrane protein 154
chr6_+_34312906 0.312 HMGA1
high mobility group AT-hook 1
chr1_-_28392966 0.311 NM_001164722
NM_001164721
PTAFR

platelet-activating factor receptor

chr3_+_42165740 0.308 TRAK1
trafficking protein, kinesin binding 1
chr7_+_128795280 0.305 AHCYL2
adenosylhomocysteinase-like 2
chr1_-_7998265 0.302 ERRFI1
ERBB receptor feedback inhibitor 1
chr20_+_42777298 0.295 NM_003881
WISP2
WNT1 inducible signaling pathway protein 2
chr19_-_60557875 0.294 NM_144613
COX6B2
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr19_+_15079141 0.293 NM_033025
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr8_+_22078622 0.293 BMP1
bone morphogenetic protein 1
chr19_-_41561904 0.292 NM_020917
ZFP14
zinc finger protein 14 homolog (mouse)
chr16_+_79132354 0.292 NM_130897
DYNLRB2
dynein, light chain, roadblock-type 2
chr10_-_73167586 0.290 NM_001168390
C10orf105
chromosome 10 open reading frame 105
chr6_+_151602787 0.288 NM_005100
AKAP12
A kinase (PRKA) anchor protein 12
chr10_+_85994788 0.287 NM_001012720
NM_001012722
NM_002921
RGR


retinal G protein coupled receptor


chr5_-_137502975 0.287 NM_003551
NME5
non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)
chr7_-_75876830 0.286 NM_080744
SRCRB4D
scavenger receptor cysteine rich domain containing, group B (4 domains)
chr6_-_41238798 0.283 TREM2
triggering receptor expressed on myeloid cells 2
chr7_-_76667045 0.283 NM_006682
FGL2
fibrinogen-like 2
chr19_-_13074973 0.283 NM_005583
LYL1
lymphoblastic leukemia derived sequence 1
chr20_+_42777419 0.282 WISP2
WNT1 inducible signaling pathway protein 2
chr12_-_55637648 0.281 NM_003708
RDH16
retinol dehydrogenase 16 (all-trans)
chr11_-_6773589 0.280 NM_003696
OR6A2
olfactory receptor, family 6, subfamily A, member 2
chr10_+_72245730 0.278 SGPL1
sphingosine-1-phosphate lyase 1
chr8_+_22078589 0.277 NM_001199
NM_006129
BMP1

bone morphogenetic protein 1

chr5_-_112658200 0.276 MCC
mutated in colorectal cancers
chr11_-_18226743 0.274 NM_001127380
NM_030754
SAA2

serum amyloid A2

chr10_+_5556923 0.274 NM_005185
CALML3
calmodulin-like 3
chr6_+_34312667 0.272 HMGA1
high mobility group AT-hook 1
chr20_-_55718351 0.271 NM_020182
PMEPA1
prostate transmembrane protein, androgen induced 1
chr11_+_117452995 0.271 TMPRSS4
transmembrane protease, serine 4
chr3_-_58627509 0.270 NM_138805
FAM3D
family with sequence similarity 3, member D
chr5_+_156625629 0.268 NM_001037333
NM_001037332
CYFIP2

cytoplasmic FMR1 interacting protein 2

chr16_+_70117523 0.267 NM_005769
NM_001166395
CHST4

carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4

chr9_+_129066576 0.267 NM_032293
GARNL3
GTPase activating Rap/RanGAP domain-like 3
chr6_+_37360144 0.264 TBC1D22B
TBC1 domain family, member 22B
chr11_+_6854431 0.261 NM_207186
OR10A4
olfactory receptor, family 10, subfamily A, member 4
chr4_+_37131946 0.260 NM_001104629
C4orf19
chromosome 4 open reading frame 19
chr11_+_117452936 0.260 NM_001083947
NM_001173551
NM_001173552
NM_019894
TMPRSS4



transmembrane protease, serine 4



chr10_+_69314714 0.260 SIRT1
sirtuin 1
chr6_+_160247962 0.259 NM_002377
MAS1
MAS1 oncogene
chr3_-_140741063 0.259 RBP1
retinol binding protein 1, cellular
chr2_+_62754489 0.258 NM_001142615
EHBP1
EH domain binding protein 1
chr10_+_43187095 0.257 NM_001184963
NM_173160
FXYD4

FXYD domain containing ion transport regulator 4

chr3_-_140741167 0.256 RBP1
retinol binding protein 1, cellular
chr10_+_63803921 0.255 NM_014951
NM_199450
NM_199451
ZNF365


zinc finger protein 365


chr1_+_154386358 0.247 NM_001193301
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr19_+_3129735 0.246 NM_003775
S1PR4
sphingosine-1-phosphate receptor 4
chr19_-_7976468 0.246 NM_001419
ELAVL1
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
chr9_+_94749421 0.240 NM_001083536
FGD3
FYVE, RhoGEF and PH domain containing 3
chr11_+_1897374 0.238 NM_001042780
NM_001042781
NM_001042782
NM_006757
TNNT3



troponin T type 3 (skeletal, fast)



chr11_-_72182291 0.238 NM_006645
STARD10
StAR-related lipid transfer (START) domain containing 10
chr11_-_66245288 0.234 NM_006946
SPTBN2
spectrin, beta, non-erythrocytic 2
chr1_-_221920023 0.234 NM_001143962
CAPN8
calpain 8
chr7_+_150180464 0.234 NM_001091
ABP1
amiloride binding protein 1 (amine oxidase (copper-containing))
chr3_+_23822481 0.232 UBE2E1
ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)
chr6_-_33822659 0.232 NM_001142883
NM_054111
IP6K3

inositol hexakisphosphate kinase 3

chr15_-_79453472 0.227 NM_001080532
TMC3
transmembrane channel-like 3
chr6_+_155579788 0.227 NM_001010927
TIAM2
T-cell lymphoma invasion and metastasis 2
chr12_-_6586736 0.224 CHD4
chromodomain helicase DNA binding protein 4
chr11_-_65182801 0.223 RELA
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
chr7_+_28497272 0.222 CREB5
cAMP responsive element binding protein 5
chr1_-_155336223 0.221 NM_001004341
ETV3L
ets variant 3-like
chr3_+_38363226 0.221 NM_005108
XYLB
xylulokinase homolog (H. influenzae)
chr22_-_37966852 0.219 NM_033016
PDGFB
platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)
chr6_-_2785682 0.218 SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr8_-_19584373 0.217 NM_018371
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr7_+_148523486 0.216 NM_003575
ZNF282
zinc finger protein 282
chr2_+_181553333 0.216 NM_182678
NM_006357
UBE2E3

ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)

chr19_-_4468715 0.216 NM_001080400
PLIN4
perilipin 4
chrX_-_52913056 0.214 NM_130776
XAGE3
X antigen family, member 3
chr6_-_25679197 0.214


chr1_+_35507145 0.214 NM_005095
ZMYM4
zinc finger, MYM-type 4
chr3_+_185232025 0.213 NM_182537
HTR3D
5-hydroxytryptamine (serotonin) receptor 3 family member D
chr9_-_125070613 0.212 NM_018387
STRBP
spermatid perinuclear RNA binding protein
chr1_+_109884016 0.212 NM_031936
GPR61
G protein-coupled receptor 61
chr9_-_125070675 0.210 NM_001171137
STRBP
spermatid perinuclear RNA binding protein
chr7_+_6380614 0.209 NM_006908
NM_018890
RAC1

ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

chr12_-_49763566 0.209 NM_030809
CSRNP2
cysteine-serine-rich nuclear protein 2
chr16_+_68238460 0.208 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr1_+_32777556 0.205 ZBTB8A
zinc finger and BTB domain containing 8A
chr16_+_8714326 0.205 NM_000663
ABAT
4-aminobutyrate aminotransferase
chr9_-_115101140 0.204 NM_145051
RNF183
ring finger protein 183
chr17_+_7328497 0.204 POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr2_+_45732416 0.204 NM_005400
PRKCE
protein kinase C, epsilon
chr15_+_88120592 0.199 NM_001039958
MESP2
mesoderm posterior 2 homolog (mouse)
chr10_-_126097483 0.198 NM_000274
NM_001171814
OAT

ornithine aminotransferase

chr10_+_86121526 0.197 FAM190B
family with sequence similarity 190, member B
chr16_-_67930907 0.196 COG8
component of oligomeric golgi complex 8
chrX_-_64055741 0.193 ZC4H2
zinc finger, C4H2 domain containing
chr19_-_54859790 0.193 IRF3
interferon regulatory factor 3
chr3_+_66527586 0.192


chr17_+_36493927 0.187 NM_033061
KRTAP4-7
keratin associated protein 4-7
chr17_-_52248248 0.187 NM_001085430
C17orf67
chromosome 17 open reading frame 67
chr9_+_136358134 0.187 NM_002957
RXRA
retinoid X receptor, alpha
chr10_+_24795446 0.187 KIAA1217
KIAA1217
chr16_+_67131161 0.185 NM_133458
ZFP90
zinc finger protein 90 homolog (mouse)
chr21_-_46528594 0.184 MCM3AP
minichromosome maintenance complex component 3 associated protein
chr6_-_32268267 0.182 GPSM3
G-protein signaling modulator 3
chrX_-_16798096 0.182 RBBP7
retinoblastoma binding protein 7
chr10_-_49483002 0.182 NM_021226
ARHGAP22
Rho GTPase activating protein 22
chr6_-_139350710 0.180 REPS1
RALBP1 associated Eps domain containing 1
chr6_+_34312979 0.178 HMGA1
high mobility group AT-hook 1
chr20_-_3710060 0.176 NM_015417
SPEF1
sperm flagellar 1
chr16_-_73859451 0.176 NM_001170715
BCAR1
breast cancer anti-estrogen resistance 1
chr17_-_31441390 0.176 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr10_-_69125932 0.175 NM_013266
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr11_+_44026106 0.175 NM_001031854
ACCSL
1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)-like
chr1_+_27591738 0.175 NM_005281
GPR3
G protein-coupled receptor 3
chr17_+_7328804 0.174


chr18_+_13208777 0.174 NM_181481
NM_181482
C18orf1

chromosome 18 open reading frame 1

chr20_+_56369012 0.173


chrX_-_19918958 0.172 LOC729609
hypothetical LOC729609
chr11_-_5657947 0.171 TRIM5
tripartite motif containing 5
chr2_+_178893216 0.170 NM_145739
OSBPL6
oxysterol binding protein-like 6
chr2_+_108271526 0.170 NM_001056
NM_176825
SULT1C2

sulfotransferase family, cytosolic, 1C, member 2

chr6_-_31740645 0.167 NM_033177
GPANK1
G patch domain and ankyrin repeats 1
chr9_+_123088217 0.167 GSN
gelsolin
chr9_+_33667169 0.167


chr17_-_3445873 0.165 NM_080705
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr3_+_38363292 0.164 XYLB
xylulokinase homolog (H. influenzae)
chr2_+_216695062 0.163 XRCC5
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
chr16_+_31105579 0.162


chr16_-_3082840 0.161 NM_032805
ZSCAN10
zinc finger and SCAN domain containing 10
chr1_-_221919982 0.160 CAPN8
calpain 8
chr7_+_128795178 0.159 NM_001130723
AHCYL2
adenosylhomocysteinase-like 2
chr11_+_116580892 0.159 TAGLN
transgelin
chr8_+_98950453 0.159 NM_002380
NM_030583
MATN2

matrilin 2

chr3_-_95175588 0.156 NM_000313
PROS1
protein S (alpha)
chr17_-_53335748 0.156 NM_017949
CUEDC1
CUE domain containing 1
chr16_+_67130616 0.155 ZFP90
zinc finger protein 90 homolog (mouse)
chr11_+_125678856 0.152 NM_014026
DCPS
decapping enzyme, scavenger
chr16_+_6473759 0.152 RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr9_+_130942029 0.152 PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr11_+_129445002 0.151 APLP2
amyloid beta (A4) precursor-like protein 2
chr11_+_35641234 0.151 TRIM44
tripartite motif containing 44
chr1_+_1104939 0.151 NM_153254
TTLL10
tubulin tyrosine ligase-like family, member 10

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.